High-pressure liquid chromatographic method for determination of rosaramicin in humans.

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High-pressure liquid chromatographic method for determination of rosaramicin in humans.

A high-pressure liquid chromatographic method has been developed for the quantitative determination of rosaramicin in serum. This procedure involves addition of an internal standard, adjustment to alkaline pH, treatment with potassium carbonate, ether extraction, and a reverse-phase column separation with acetonitrile-acetate buffer mixture as the mobile phase. This technique produces a good li...

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ژورنال

عنوان ژورنال: Antimicrobial Agents and Chemotherapy

سال: 1980

ISSN: 0066-4804,1098-6596

DOI: 10.1128/aac.18.5.780